1gmy

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Image:1gmy.png

Template:STRUCTURE 1gmy

CATHEPSIN B COMPLEXED WITH DIPEPTIDYL NITRILE INHIBITOR

Template:ABSTRACT PUBMED 11741472

About this Structure

1GMY is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Greenspan PD, Clark KL, Tommasi RA, Cowen SD, McQuire LW, Farley DL, van Duzer JH, Goldberg RL, Zhou H, Du Z, Fitt JJ, Coppa DE, Fang Z, Macchia W, Zhu L, Capparelli MP, Goldstein R, Wigg AM, Doughty JR, Bohacek RS, Knap AK. Identification of dipeptidyl nitriles as potent and selective inhibitors of cathepsin B through structure-based drug design. J Med Chem. 2001 Dec 20;44(26):4524-34. PMID:11741472

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