3cki
From Proteopedia
Contents |
Crystal structure of the TACE-N-TIMP-3 complex
Template:ABSTRACT PUBMED 18638486
Disease
Known disease associated with this structure: Sorsby fundus dystrophy OMIM:[188826]
About this Structure
3CKI is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wisniewska M, Goettig P, Maskos K, Belouski E, Winters D, Hecht R, Black R, Bode W. Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex. J Mol Biol. 2008 Sep 19;381(5):1307-19. Epub 2008 Jul 7. PMID:18638486 doi:10.1016/j.jmb.2008.06.088
Page seeded by OCA on Tue Feb 17 20:14:14 2009
Categories: ADAM 17 endopeptidase | Homo sapiens | Belouski, E. | Black, R. | Bode, W. | Goettig, P. | Hecht, R. | Maskos, K. | Winters, D. | Wisniewska, M. | Alternative splicing | Catalytic zinc | Cleavage on pair of basic residue | Disease mutation | Extra-cellular matrix | Extracellular matrix | Glycoprotein | Hydrolase | Hydrolase inhibitor | Membrane | Metal-binding | Metalloenzyme inhibitor | Metalloprotease | Metalloprotease inhibitor | Notch signaling pathway | Phosphoprotein | Protease | Sa-sb loop | Secreted | Sensory transduction | Sh3-binding | Transmembrane | Vision | Zymogen