3d5q

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Template:STRUCTURE 3d5q

Crystal Structure of 11b-HSD1 in Complex with Triazole Inhibitor

Template:ABSTRACT PUBMED 18789704

About this Structure

3D5Q is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tu H, Powers JP, Liu J, Ursu S, Sudom A, Yan X, Xu H, Meininger D, Degraffenreid M, He X, Jaen JC, Sun D, Labelle M, Yamamoto H, Shan B, Walker NP, Wang Z. Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. Bioorg Med Chem. 2008 Oct 1;16(19):8922-31. Epub 2008 Aug 29. PMID:18789704 doi:10.1016/j.bmc.2008.08.065

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