2bre

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Image:2bre.png

Template:STRUCTURE 2bre

STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90.

Template:ABSTRACT PUBMED 15955698

About this Structure

2BRE is a 2 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Cheung KM, Matthews TP, James K, Rowlands MG, Boxall KJ, Sharp SY, Maloney A, Roe SM, Prodromou C, Pearl LH, Aherne GW, McDonald E, Workman P. The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorg Med Chem Lett. 2005 Jul 15;15(14):3338-43. PMID:15955698 doi:10.1016/j.bmcl.2005.05.046

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