This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2gs2

From Proteopedia

Revision as of 18:55, 17 February 2009 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2gs2.png

Template:STRUCTURE 2gs2

Contents

Crystal Structure of the active EGFR kinase domain

Template:ABSTRACT PUBMED 16777603

Disease

Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]

About this Structure

2GS2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhang X, Gureasko J, Shen K, Cole PA, Kuriyan J. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell. 2006 Jun 16;125(6):1137-49. PMID:16777603 doi:10.1016/j.cell.2006.05.013

Page seeded by OCA on Tue Feb 17 20:55:07 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2gs2"
Personal tools