1ijr

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Template:STRUCTURE 1ijr

Crystal structure of LCK SH2 complexed with nonpeptide phosphotyrosine mimetic

Template:ABSTRACT PUBMED 11527723

About this Structure

1IJR is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kawahata N, Yang MG, Luke GP, Shakespeare WC, Sundaramoorthi R, Wang Y, Johnson D, Merry T, Violette S, Guan W, Bartlett C, Smith J, Hatada M, Lu X, Dalgarno DC, Eyermann CJ, Bohacek RS, Sawyer TK. A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2319-23. PMID:11527723

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