1jcr

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Image:1jcr.png

Template:STRUCTURE 1jcr

CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE

Template:ABSTRACT PUBMED 11687658

About this Structure

1JCR is a 3 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Long SB, Hancock PJ, Kral AM, Hellinga HW, Beese LS. The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12948-53. Epub 2001 Oct 30. PMID:11687658 doi:10.1073/pnas.241407898

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