2f3f

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Image:2f3f.png

Template:STRUCTURE 2f3f

Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor

Template:ABSTRACT PUBMED 16854060

About this Structure

2F3F is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M. Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J Med Chem. 2006 Jul 27;49(15):4544-67. PMID:16854060 doi:10.1021/jm060154a

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