3cwb

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Image:3cwb.png

Template:STRUCTURE 3cwb

Chicken Cytochrome BC1 Complex inhibited by an iodinated analogue of the polyketide Crocacin-D

Template:ABSTRACT PUBMED 18996700

About this Structure

3CWB is a 20 chains structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Crowley PJ, Berry EA, Cromartie T, Daldal F, Godfrey CR, Lee DW, Phillips JE, Taylor A, Viner R. The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D. Bioorg Med Chem. 2008 Dec 15;16(24):10345-55. Epub 2008 Oct 17. PMID:18996700 doi:10.1016/j.bmc.2008.10.030
  • Zhang Z, Huang L, Shulmeister VM, Chi YI, Kim KK, Hung LW, Crofts AR, Berry EA, Kim SH. Electron transfer by domain movement in cytochrome bc1. Nature. 1998 Apr 16;392(6677):677-84. PMID:9565029 doi:10.1038/33612
  • Huang LS, Cobessi D, Tung EY, Berry EA. Binding of the respiratory chain inhibitor antimycin to the mitochondrial bc1 complex: a new crystal structure reveals an altered intramolecular hydrogen-bonding pattern. J Mol Biol. 2005 Aug 19;351(3):573-97. PMID:16024040 doi:10.1016/j.jmb.2005.05.053

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