1m54

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Image:1m54.png

Template:STRUCTURE 1m54

Contents

CYSTATHIONINE-BETA SYNTHASE: REDUCED VICINAL THIOLS

Template:ABSTRACT PUBMED 12173932

Disease

Known disease associated with this structure: Homocystinuria, B6-responsive and nonresponsive types OMIM:[236200], Thrombosis, hyperhomocysteinemic OMIM:[236200]

About this Structure

1M54 is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Taoka S, Lepore BW, Kabil O, Ojha S, Ringe D, Banerjee R. Human cystathionine beta-synthase is a heme sensor protein. Evidence that the redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in the crystal structure of the truncated enzyme. Biochemistry. 2002 Aug 20;41(33):10454-61. PMID:12173932

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