2bio

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Image:2bio.png

Template:STRUCTURE 2bio

HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-N239Y-R249S-N268D

Template:ABSTRACT PUBMED 15703170

About this Structure

2BIO is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Joerger AC, Ang HC, Veprintsev DB, Blair CM, Fersht AR. Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations. J Biol Chem. 2005 Apr 22;280(16):16030-7. Epub 2005 Feb 9. PMID:15703170 doi:http://dx.doi.org/10.1074/jbc.M500179200

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