2qwh

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Template:STRUCTURE 2qwh

THE X-RAY STRUCTURE OF A COMPLEX OF 5-N-ACETYL-5-AMINO-3-(1-ETHYLPROPOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID (GS4071) AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

Template:ABSTRACT PUBMED 9655825

About this Structure

2QWH is a 1 chain structure of sequence from Influenza a virus. Full crystallographic information is available from OCA.

Reference

  • Varghese JN, Smith PW, Sollis SL, Blick TJ, Sahasrabudhe A, McKimm-Breschkin JL, Colman PM. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure. 1998 Jun 15;6(6):735-46. PMID:9655825

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