1o5m

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Image:1o5m.png

Template:STRUCTURE 1o5m

Structure of FPT bound to the inhibitor SCH66336

Template:ABSTRACT PUBMED 10377218

About this Structure

1O5M is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Strickland CL, Weber PC, Windsor WT, Wu Z, Le HV, Albanese MM, Alvarez CS, Cesarz D, del Rosario J, Deskus J, Mallams AK, Njoroge FG, Piwinski JJ, Remiszewski S, Rossman RR, Taveras AG, Vibulbhan B, Doll RJ, Girijavallabhan VM, Ganguly AK. Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships. J Med Chem. 1999 Jun 17;42(12):2125-35. PMID:10377218 doi:http://dx.doi.org/10.1021/jm990030g

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