2r0o

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Image:2r0o.png

Template:STRUCTURE 2r0o

Contents

Crystal structure of the actin-binding domain of human alpha-actinin-4 mutant(K255E)

Template:ABSTRACT PUBMED 18164029

Disease

Known disease associated with this structure: Glomerulosclerosis, focal segmental, 1 OMIM:[604638]

About this Structure

2R0O is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lee SH, Weins A, Hayes DB, Pollak MR, Dominguez R. Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis. J Mol Biol. 2008 Feb 15;376(2):317-24. Epub 2007 Dec 4. PMID:18164029 doi:10.1016/j.jmb.2007.11.084

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