We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

2fvd

From Proteopedia

Revision as of 03:11, 18 February 2009 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2fvd.png

Template:STRUCTURE 2fvd

Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor

Template:ABSTRACT PUBMED 17064073

About this Structure

2FVD is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chu XJ, DePinto W, Bartkovitz D, So SS, Vu BT, Packman K, Lukacs C, Ding Q, Jiang N, Wang K, Goelzer P, Yin X, Smith MA, Higgins BX, Chen Y, Xiang Q, Moliterni J, Kaplan G, Graves B, Lovey A, Fotouhi N. Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-diflu oro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity. J Med Chem. 2006 Nov 2;49(22):6549-60. PMID:17064073 doi:10.1021/jm0606138

Page seeded by OCA on Wed Feb 18 05:11:43 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2fvd"
Personal tools