3dxj

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Template:STRUCTURE 3dxj

Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin

Template:ABSTRACT PUBMED 18957204

About this Structure

3DXJ is a 12 chains structure of sequences from Thermus thermophilus hb8. Full crystallographic information is available from OCA.

Reference

  • Mukhopadhyay J, Das K, Ismail S, Koppstein D, Jang M, Hudson B, Sarafianos S, Tuske S, Patel J, Jansen R, Irschik H, Arnold E, Ebright RH. The RNA polymerase "switch region" is a target for inhibitors. Cell. 2008 Oct 17;135(2):295-307. PMID:18957204 doi:10.1016/j.cell.2008.09.033

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