2bnl

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2bnl, resolution 2.00Å

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THE STRUCTURE OF THE N-TERMINAL DOMAIN OF RSBR

Overview

RsbR is a regulator of sigma(B), the RNA polymerase sigma factor subunit, responsible for transcribing the general stress response genes when, environmental stress is imposed on Bacillus subtilis. The C-terminal, domain of RsbR and its paralogues is a substrate for the kinase function, of another sigma(B) regulator, RsbT, but the amino acid sequence of the, N-terminal domain of RsbR does not reveal any obvious biochemical, function. RsbR, its paralogues, and other regulators of sigma(B), including RsbS and RsbT, form large signaling complexes, called, stressosomes. We have determined and present here the crystal structure of, the N-terminal domain of RsbR. Unexpectedly, this structure belongs to the, globin fold superfamily, but there is no bound cofactor. The globin domain, from ... [(full description)]

About this Structure

2BNL is a [Single protein] structure of sequence from [Bacillus subtilis] with NA as [ligand]. Full crystallographic information is available from [OCA].

Reference

Structure of a nonheme globin in environmental stress signaling., Murray JW, Delumeau O, Lewis RJ, Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17320-5. Epub 2005 Nov 21. PMID:16301540

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