This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2fir
From Proteopedia
| |||||||||
| 2fir, resolution 2.00Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , , | ||||||||
| Non-Standard Residues: | |||||||||
| Gene: | F7 (Homo sapiens), F3 (Homo sapiens) | ||||||||
| Activity: | Coagulation factor VIIa, with EC number 3.4.21.21 | ||||||||
| Related: | 1dan, 2a2q, 2aer, 2b8o | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Crystal structure of DFPR-VIIa/sTF
Template:ABSTRACT PUBMED 16757484
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
2FIR is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484 doi:10.1074/jbc.M509971200
Page seeded by OCA on Wed Feb 18 06:43:37 2009
