2hiw

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Image:2hiw.png

Template:STRUCTURE 2hiw

Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor

Template:ABSTRACT PUBMED 16873026

About this Structure

2HIW is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Okram B, Nagle A, Adrian FJ, Lee C, Ren P, Wang X, Sim T, Xie Y, Wang X, Xia G, Spraggon G, Warmuth M, Liu Y, Gray NS. A general strategy for creating "inactive-conformation" abl inhibitors. Chem Biol. 2006 Jul;13(7):779-86. PMID:16873026 doi:10.1016/j.chembiol.2006.05.015

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