1t4f
From Proteopedia
Structure of human MDM2 in complex with an optimized p53 peptide
Template:ABSTRACT PUBMED 15715460
About this Structure
1T4F is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF. Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells. J Med Chem. 2005 Feb 24;48(4):909-12. PMID:15715460 doi:10.1021/jm049137g
Page seeded by OCA on Wed Feb 18 07:49:25 2009
