2f9b

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Image:2f9b.png

Template:STRUCTURE 2f9b

Contents

Discovery of Novel Heterocyclic Factor VIIa Inhibitors

Template:ABSTRACT PUBMED 16460932

Disease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]

About this Structure

2F9B is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rai R, Kolesnikov A, Sprengeler PA, Torkelson S, Ton T, Katz BA, Yu C, Hendrix J, Shrader WD, Stephens R, Cabuslay R, Sanford E, Young WB. Discovery of novel heterocyclic factor VIIa inhibitors. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2270-3. Epub 2006 Feb 3. PMID:16460932 doi:10.1016/j.bmcl.2006.01.017

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