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2f9b
From Proteopedia
Contents |
Discovery of Novel Heterocyclic Factor VIIa Inhibitors
Template:ABSTRACT PUBMED 16460932
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
2F9B is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rai R, Kolesnikov A, Sprengeler PA, Torkelson S, Ton T, Katz BA, Yu C, Hendrix J, Shrader WD, Stephens R, Cabuslay R, Sanford E, Young WB. Discovery of novel heterocyclic factor VIIa inhibitors. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2270-3. Epub 2006 Feb 3. PMID:16460932 doi:10.1016/j.bmcl.2006.01.017
Page seeded by OCA on Wed Feb 18 07:53:56 2009
Categories: Coagulation factor VIIa | Homo sapiens | Cabuslay, R. | Hendrix, J. | Katz, B A. | Kolesnikov, A. | Rai, R. | Sanford, E. | Shrader, W D. | Sprengeler, P A. | Stephens, R. | Ton, T. | Torkelson, S. | Young, W B. | Yu, C. | Active site-directed inhibitor | Serine protease | Short hydrogen bond
