2rbe

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Image:2rbe.png

Template:STRUCTURE 2rbe

The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors

Template:ABSTRACT PUBMED 17919905

About this Structure

2RBE is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yuan C, St Jean DJ Jr, Liu Q, Cai L, Li A, Han N, Moniz G, Askew B, Hungate RW, Johansson L, Tedenborg L, Pyring D, Williams M, Hale C, Chen M, Cupples R, Zhang J, Jordan S, Bartberger MD, Sun Y, Emery M, Wang M, Fotsch C. The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6056-61. Epub 2007 Sep 25. PMID:17919905 doi:10.1016/j.bmcl.2007.09.070

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