1nvu

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Image:1nvu.png

Template:STRUCTURE 1nvu

Contents

Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS

Template:ABSTRACT PUBMED 12628188

Disease

Known disease associated with this structure: Fibromatosis, gingival OMIM:[182530], Noonan syndrome 4 OMIM:[182530]

About this Structure

1NVU is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 2003 Mar 7;112(5):685-95. PMID:12628188

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