1y0w

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Template:STRUCTURE 1y0w

Contents 1 T-to-THigh quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (10 test sets) 2 Disease 3 About this Structure 4 Reference

T-to-THigh quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (10 test sets)

Template:ABSTRACT PUBMED 15835899

Disease

Known disease associated with this structure: Erythremias, alpha- OMIM:[141800], Heinz body anemias, alpha- OMIM:[141800], Methemoglobinemias, alpha- OMIM:[141800], Thalassemias, alpha- OMIM:[141800], Erythremias, beta- OMIM:[141900], Heinz body anemias, beta- OMIM:[141900], Hereditary persistence of fetal hemoglobin OMIM:[141900], Methemoglobinemias, beta- OMIM:[141900], Sickle cell anemia OMIM:[141900], Thalassemia-beta, dominant inclusion-body OMIM:[141900], Thalassemias, beta- OMIM:[141900]

About this Structure

1Y0W is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Kavanaugh JS, Rogers PH, Arnone A. Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry. 2005 Apr 26;44(16):6101-21. PMID:15835899 doi:http://dx.doi.org/10.1021/bi047813a

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