2hk5

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Image:2hk5.png

Template:STRUCTURE 2hk5

Hck Kinase in Complex with Lck targetted Inhibitor PG-1009247

Template:ABSTRACT PUBMED 16997556

About this Structure

2HK5 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sabat M, VanRens JC, Laufersweiler MJ, Brugel TA, Maier J, Golebiowski A, De B, Easwaran V, Hsieh LC, Walter RL, Mekel MJ, Evdokimov A, Janusz MJ. The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck). Bioorg Med Chem Lett. 2006 Dec 1;16(23):5973-7. Epub 2006 Sep 25. PMID:16997556 doi:10.1016/j.bmcl.2006.08.132

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