1svh

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Image:1svh.png

Template:STRUCTURE 1svh

Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 8

Template:ABSTRACT PUBMED 14998327

About this Structure

1SVH is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Breitenlechner CB, Wegge T, Berillon L, Graul K, Marzenell K, Friebe WG, Thomas U, Schumacher R, Huber R, Engh RA, Masjost B. Structure-based optimization of novel azepane derivatives as PKB inhibitors. J Med Chem. 2004 Mar 11;47(6):1375-90. PMID:14998327 doi:http://dx.doi.org/10.1021/jm0310479

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