2zb2
From Proteopedia
Contents |
Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide
Template:ABSTRACT PUBMED 18434170
Disease
Known disease associated with this structure: Glycogen storage disease VI OMIM:[232700]
About this Structure
2ZB2 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Onda K, Suzuki T, Shiraki R, Yonetoku Y, Negoro K, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S. Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a. Bioorg Med Chem. 2008 May 15;16(10):5452-64. Epub 2008 Apr 11. PMID:18434170 doi:10.1016/j.bmc.2008.04.010
Page seeded by OCA on Wed Feb 18 09:29:12 2009
Categories: Homo sapiens | Phosphorylase | Katayama, N. | Onda, K. | Acetylation | Allosteric binding | Allosteric enzyme | Allosteric site | Carbohydrate metabolism | Disease mutation | Glycogen metabolism | Glycogen storage disease | Glycosyltransferase | Nucleotide-binding | Phosphorylation | Polymorphism | Pyridoxal phosphate | Transferase