1nk5

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Image:1nk5.png

Template:STRUCTURE 1nk5

ADENINE-ADENINE MISMATCH AT THE POLYMERASE ACTIVE SITE

Template:ABSTRACT PUBMED 15035983

About this Structure

1NK5 is a 3 chains structure of sequences from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

  • Johnson SJ, Beese LS. Structures of mismatch replication errors observed in a DNA polymerase. Cell. 2004 Mar 19;116(6):803-16. PMID:15035983
  • Johnson SJ, Taylor JS, Beese LS. Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3895-900. Epub 2003 Mar 20. PMID:12649320 doi:http://dx.doi.org/10.1073/pnas.0630532100

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