1ly4

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Image:1ly4.png

Template:STRUCTURE 1ly4

Analysis of quinazoline and PYRIDO[2,3D]PYRIMIDINE N9-C10 reversed bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase

Template:ABSTRACT PUBMED 12198294

About this Structure

1LY4 is a 1 chain structure of sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

Reference

  • Cody V, Galitsky N, Luft JR, Pangborn W, Queener SF, Gangjee A. Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase. Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1393-9. Epub 2002, Aug 23. PMID:12198294 doi:10.1107/S0907444902010442

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