3e34

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Image:3e34.jpg

Template:STRUCTURE 3e34

Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10

Template:ABSTRACT PUBMED 19246009

About this Structure

3E34 is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Hast MA, Fletcher S, Cummings CG, Pusateri EE, Blaskovich MA, Rivas K, Gelb MH, Van Voorhis WC, Sebti SM, Hamilton AD, Beese LS. Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem Biol. 2009 Feb 27;16(2):181-92. PMID:19246009 doi:10.1016/j.chembiol.2009.01.014

Page seeded by OCA on Wed Mar 11 11:25:14 2009

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