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Triose Phosphate Isomerase
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Triose Phosphate Isomerase
Image:TPIstructure.jpg prions.com
Contents |
Overview
(TPI or TIM) which catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate, an essential process in the glycolytic pathway.
Mechanism
TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction. This isomerization of a ketose to an aldose proceeds through an enediol intermediate.<Biochemistry 6th Edition>
Acid Base Catalysis
Diagram .<ref name= "web.virginia.edu" [1]
Structure & Function
Disease
Triose Phosphate Isomerase Deficiency
See Also
References For further information on Triose Phosphate Isomerase
Triosephosphate isomerase deficiency
Berg, Jeremy M. Sryer, Lubert. Tymoczko, John L. Biochemistry: 6th Edition. W.H Freedman and Company (2007)
Proteopedia Page Contributors and Editors (what is this?)
Gregg Snider, Eric Martz, Michal Harel, Alexander Berchansky, David Canner, Eran Hodis, Stephen Everse, Angel Herraez, Jane S. Richardson
![[1]](http://web.virginia.edu/Heidi/chapter19/Images/8883n19_15.jpg){kind=link}