3c08

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Image:3c08.png

Template:STRUCTURE 3c08

Crystal structure the Fab fragment of matuzumab/EMD72000 (Fab72000)

Template:ABSTRACT PUBMED 18394559

About this Structure

3C08 is a 2 chains structure of sequences from Homo sapiens, mus musculus. Full crystallographic information is available from OCA.

Reference

  • Schmiedel J, Blaukat A, Li S, Knochel T, Ferguson KM. Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell. 2008 Apr;13(4):365-73. PMID:18394559 doi:10.1016/j.ccr.2008.02.019

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