2jit

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Image:2jit.png

Template:STRUCTURE 2jit

CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION

Template:ABSTRACT PUBMED 18227510

About this Structure

2JIT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2070-5. Epub 2008 Jan 28. PMID:18227510

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