2isl

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Image:2isl.png

Template:STRUCTURE 2isl

BluB bound to reduced flavin (FMNH2) and molecular oxygen. (clear crystal form)

Template:ABSTRACT PUBMED 17377583

About this Structure

2ISL is a 8 chains structure of sequences from Sinorhizobium meliloti. Full crystallographic information is available from OCA.

Reference

  • Taga ME, Larsen NA, Howard-Jones AR, Walsh CT, Walker GC. BluB cannibalizes flavin to form the lower ligand of vitamin B12. Nature. 2007 Mar 22;446(7134):449-53. PMID:17377583 doi:10.1038/nature05611
  • Campbell GR, Taga ME, Mistry K, Lloret J, Anderson PJ, Roth JR, Walker GC. Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4634-9. Epub 2006 Mar 1. PMID:16537439

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