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3c2z

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Template:STRUCTURE 3c2z

tRNA-Guanine Transglycosylase (TGT) in complex with 6-Amino-2-[(thiophen-2-ylmethyl)-amino]-1,7-dihydro-imidazo[4,5-g]quinazolin-8-one

Template:ABSTRACT PUBMED 19199329

About this Structure

3C2Z is a 1 chain structure of sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

  • Ritschel T, Hoertner S, Heine A, Diederich F, Klebe G. Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT. Chembiochem. 2009 Mar 2;10(4):716-27. PMID:19199329 doi:10.1002/cbic.200800782

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