3g6h

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Template:STRUCTURE 3g6h

Src Thr338Ile inhibited in the DFG-Asp-Out conformation

Template:ABSTRACT PUBMED 19276351

About this Structure

3G6H is a 2 chains structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Seeliger MA, Ranjitkar P, Kasap C, Shan Y, Shaw DE, Shah NP, Kuriyan J, Maly DJ. Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations. Cancer Res. 2009 Mar 15;69(6):2384-92. Epub 2009 Mar 10. PMID:19276351 doi:10.1158/0008-5472.CAN-08-3953

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