2wc0

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Image:2wc0.png

Template:STRUCTURE 2wc0

CRYSTAL STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH IODINATED INSULIN

Template:ABSTRACT PUBMED 19321446

About this Structure

2WC0 is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Manolopoulou M, Guo Q, Malito E, Schilling AB, Tang WJ. Molecular basis of catalytic chamber-assisted unfolding and cleavage of human insulin by human insulin-degrading enzyme. J Biol Chem. 2009 May 22;284(21):14177-88. Epub 2009 Mar 25. PMID:19321446 doi:10.1074/jbc.M900068200

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