2waf

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Image:2waf.png

Template:STRUCTURE 2waf

PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN R6)

Template:ABSTRACT PUBMED 19233207

About this Structure

2WAF is a 1 chain structure of sequence from Streptococcus pneumoniae. Full crystallographic information is available from OCA.

Reference

  • Contreras-Martel C, Dahout-Gonzalez C, Martins Ados S, Kotnik M, Dessen A. PBP active site flexibility as the key mechanism for beta-lactam resistance in pneumococci. J Mol Biol. 2009 Apr 10;387(4):899-909. Epub 2009 Feb 20. PMID:19233207 doi:10.1016/j.jmb.2009.02.024
  • Pagliero E, Chesnel L, Hopkins J, Croize J, Dideberg O, Vernet T, Di Guilmi AM. Biochemical characterization of Streptococcus pneumoniae penicillin-binding protein 2b and its implication in beta-lactam resistance. Antimicrob Agents Chemother. 2004 May;48(5):1848-55. PMID:15105143

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