2k9e

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Template:STRUCTURE 2k9e

NMR Solution Structure for ShK-192: A Potent KV1.3-Specific Immunosuppressive Polypeptide

Template:ABSTRACT PUBMED 19122005

About this Structure

2K9E is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Pennington MW, Beeton C, Galea CA, Smith BJ, Chi V, Monaghan KP, Garcia A, Rangaraju S, Giuffrida A, Plank D, Crossley G, Nugent D, Khaytin I, Lefievre Y, Peshenko I, Dixon C, Chauhan S, Orzel A, Inoue T, Hu X, Moore RV, Norton RS, Chandy KG. Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes. Mol Pharmacol. 2009 Apr;75(4):762-73. Epub 2009 Jan 2. PMID:19122005 doi:10.1124/mol.108.052704

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