3g4a

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Image:3g4a.jpg

Template:STRUCTURE 3g4a

Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution

About this Structure

3G4A is a 4 chains structure of sequences from Thermotoga maritima msb8. Full crystallographic information is available from OCA.

Reference

  • Mathews II, Deacon AM, Canaves JM, McMullan D, Lesley SA, Agarwalla S, Kuhn P. Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-complementing protein. Structure. 2003 Jun;11(6):677-90. PMID:12791256
  • Agrawal N, Lesley SA, Kuhn P, Kohen A. Mechanistic studies of a flavin-dependent thymidylate synthase. Biochemistry. 2004 Aug 17;43(32):10295-301. PMID:15301527 doi:10.1021/bi0490439

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