2np8

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Image:2np8.png

Template:STRUCTURE 2np8

Contents

Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors

Template:ABSTRACT PUBMED 17157005

Disease

Known disease associated with this structure: Colon cancer, susceptibility to OMIM:[603072]

About this Structure

2NP8 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV. Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. Epub 2006 Nov 2. PMID:17157005 doi:http://dx.doi.org/10.1016/j.bmcl.2006.10.086

Page seeded by OCA on Sun Apr 19 08:43:25 2009

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