3cxc

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Image:3cxc.jpg

Template:STRUCTURE 3cxc

The structure of an enhanced oxazolidinone inhibitor bound to the 50S ribosomal subunit of H. marismortui

Template:ABSTRACT PUBMED 18947996

About this Structure

3CXC is a 30 chains structure of sequences from Haloarcula marismortui. Full crystallographic information is available from OCA.

Reference

  • Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, Wang D, Wu Y, Johnson G. Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6175-8. Epub 2008 Oct 7. PMID:18947996 doi:10.1016/j.bmcl.2008.10.011

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