3gdx

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Image:3gdx.jpg

Template:STRUCTURE 3gdx

Dna polymerase beta with a gapped DND substrate and dTMP(CF2)PP

Template:ABSTRACT PUBMED 19351147

About this Structure

3GDX is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Upton TG, Kashemirov BA, McKenna CE, Goodman MF, Prakash GK, Kultyshev R, Batra VK, Shock DD, Pedersen LC, Beard WA, Wilson SH. Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function. Org Lett. 2009 May 7;11(9):1883-6. PMID:19351147 doi:10.1021/ol701755k

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