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3eoa

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Image:3eoa.png

Template:STRUCTURE 3eoa

Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I

Template:ABSTRACT PUBMED 19258452

About this Structure

3EOA is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Li S, Wang H, Peng B, Zhang M, Zhang D, Hou S, Guo Y, Ding J. Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4349-54. Epub 2009 Mar 3. PMID:19258452

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