3fl8

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Image:3fl8.png

Template:STRUCTURE 3fl8

Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative

Template:ABSTRACT PUBMED 19364848

About this Structure

3FL8 is a 8 chains structure of sequences from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

  • Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul;53(7):3065-73. Epub 2009 Apr 13. PMID:19364848 doi:10.1128/AAC.01666-08

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