3e1i

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Template:STRUCTURE 3e1i

Contents 1 Crystal Structure of BbetaD432A Variant Fibrinogen Fragment D with the Peptide Ligand Gly-His-Arg-Pro-amide 2 Disease 3 About this Structure 4 Reference

Crystal Structure of BbetaD432A Variant Fibrinogen Fragment D with the Peptide Ligand Gly-His-Arg-Pro-amide

Template:ABSTRACT PUBMED 19075185

Disease

Known disease associated with this structure: Afibrinogenemia, congenital OMIM:[134820], Amyloidosis, hereditary renal OMIM:[134820], Dysfibrinogenemia, alpha type, causing bleeding diathesis OMIM:[134820], Dysfibrinogenemia, alpha type, causing recurrent thrombosis OMIM:[134820], Afibrinogenemia, congenital OMIM:[134830], Dysfibrinogenemia, beta type OMIM:[134830], Thrombophilia, dysfibrinogenemic OMIM:[134830]

About this Structure

3E1I is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Bowley SR, Lord ST. Fibrinogen variant BbetaD432A has normal polymerization but does not bind knob "B". Blood. 2009 Apr 30;113(18):4425-30. Epub 2008 Dec 15. PMID:19075185 doi:10.1182/blood-2008-09-178178

Page seeded by OCA on Wed May 13 08:50:35 2009