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3dk1

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Template:STRUCTURE 3dk1

Wild Type HIV-1 Protease with potent Antiviral inhibitor GRL-0105A

Template:ABSTRACT PUBMED 18843400

About this Structure

3DK1 is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Ghosh AK, Gemma S, Takayama J, Baldridge A, Leshchenko-Yashchuk S, Miller HB, Wang YF, Kovalevsky AY, Koh Y, Weber IT, Mitsuya H. Potent HIV-1 protease inhibitors incorporating meso-bicyclic urethanes as P2-ligands: structure-based design, synthesis, biological evaluation and protein-ligand X-ray studies. Org Biomol Chem. 2008 Oct 21;6(20):3703-13. Epub 2008 Aug 11. PMID:18843400 doi:10.1039/b809178a

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