3g76

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Image:3g76.jpg

Template:STRUCTURE 3g76

Contents

Crystal structure of XIAP-BIR3 in complex with a bivalent compound

Template:ABSTRACT PUBMED 19393243

Disease

Known disease associated with this structure: Lymphoproliferative syndrome, X-linked, 2 OMIM:[300079]

About this Structure

3G76 is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cossu F, Milani M, Mastrangelo E, Vachette P, Servida F, Lecis D, Canevari G, Delia D, Drago C, Rizzo V, Manzoni L, Seneci P, Scolastico C, Bolognesi M. Structural basis for bivalent Smac-mimetics recognition in the IAP protein family. J Mol Biol. 2009 Sep 25;392(3):630-44. Epub 2009 Apr 22. PMID:19393243 doi:10.1016/j.jmb.2009.04.033

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