User:Wayne Decatur/Generate Unfolded Structures

From Proteopedia

This describes how to unfold whole or parts of chains in solved structures using Pymol.

This came up because Adrianna wanted to generate structures derived from hers where parts were unfolded or folded differently. I thought this could very useful for illustrative purposes for many users. For maybe simulating denaturing or other dynamic processes.

Please note this will generate a structure that is just for representational purposes and is not thermodynamically stable. To translate or rotate a chain or parts relative the rest of the structure see my page on moving parts or components of structures using Pymol.

Add information on breaking disulfides first and reforming others.

Pages with supporting information:

• Modeling and Editing Structures Page at Pymol Wiki
• Posting about using Sculpting in Pymol to manipulate structures

Add link to bottom part of my Morphing page because might want to let Morphing server generate structures transitioning between the folded and modified states for making an animation.